carnosine.tv
Home › Research › Dubois 2017

N-acetylcarnosine (NAC) drops for age-related cataract

Dubois VD, Bastawrous A. Cochrane Database of Systematic Reviews, 2017; 2(2):CD009493.

ReviewHumansWith N-acetylcarnosine (carnosine prodrug) eye drops

This study tested carnosine together with N-acetylcarnosine (carnosine prodrug) eye drops. Its results cannot be assigned to carnosine alone. More combination studies.

Design
Review
Subjects
2 potentially eligible studies, 114 people aged 55 to 80
Dose used in the study
Not applicable (systematic review)
Duration
Included studies ran 4 months, 6 months and 2 years
What was measured
Randomised or quasi-randomised trials of N-acetylcarnosine drops versus control in age-related cataract. Searches to 28 June 2016.

What the authors reported

Two potentially eligible studies were found, one from Russia and one from the United States. The reviewers could not get enough information to judge how the studies were designed or conducted, and classified both as awaiting classification. They concluded there is currently no convincing evidence that N-acetylcarnosine drops reverse or prevent cataract progression.

Limits of this study

No data could be pooled. Both candidate studies are classed as awaiting classification because the reviewers could not get enough information on their design, and the authors had not replied when the review was written. Full text not read.

Source

PubMed 28245346 · doi:10.1002/14651858.CD009493.pub2

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.