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Evaluation of the efficacy of Lactigo topical gel as an ergogenic aid

Sharpe TM, Macias CJ. Journal of Exercise Physiology Online, 2016; 19(3):15-23.

Open-label, no control groupHumansTopicalWith LactiGo gel (carnosine-magnesium complex) applied over a warm-up cream

This study tested carnosine together with LactiGo gel (carnosine-magnesium complex) applied over a warm-up cream. Its results cannot be assigned to carnosine alone. More combination studies.

Design
Open-label, no control group
Subjects
11 male soccer players from Italian teams, aged 22.5 plus or minus 2.1 years
Dose used in the study
10 mL of gel applied 45 minutes before testing
Duration
three test conditions separated by 3-day washouts
What was measured
Yo-Yo Intermittent Recovery Test Level 1 distance and all-out 3 x 1000 m run time under three conditions: no cream, warm-up cream, warm-up cream plus LactiGo.

What the authors reported

The authors report Yo-Yo distance of 1606 plus or minus 129 m with no cream versus 1690 plus or minus 125 m with gel (P=0.069), and 3 x 1000 m time of 248.8 plus or minus 9.6 s versus 239.7 plus or minus 12.6 s (P=0.036). Percentage changes in the abstract and in Table 2 do not match.

Limits of this study

No placebo gel and no blinding described. Eleven athletes. Carnosine was not measured in muscle or plasma. Both authors are named inventors on the LactiGo patent. Online journal; the University of Western States describes it as peer-reviewed.

Source

No PubMed record or DOI. See the citation above.

Entry checked against full text (Academia.edu copy); context from University of Western States blog on 2026-10-11. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.