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Cellular localization of carnosine-like and anserine-like immunoreactivities in rodent and avian central nervous system

Biffo S, Grillo M, Margolis FL. Neuroscience, 1990; 35(3):637-651.

Laboratory studyOther animals

Design
Laboratory study
What was measured
Production and characterisation of antisera against carnosine and anserine, and immunolocalisation of the dipeptides in rodent and avian central nervous system together with chemical analysis of brain regions.

What the authors reported

The anserine antiserum was specific while the carnosine antiserum cross-reacted with carnosine, homocarnosine and anserine. Carnosine immunoreactivity in the olfactory system was confined to mature olfactory receptor neurons, their axons and glomerular terminals; elsewhere in rodent brain, astrocytes and Bergmann glia accounted for the staining. In birds, anserine-like immunoreactivity was widespread and glial. Olfactory receptor neurons appear to be the only neurons expressing carnosine.

Limits of this study

Descriptive immunohistochemistry in rodents and birds. Abstract only.

Source

PubMed 2199844 · doi:10.1016/0306-4522(90)90335-2

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.