The histidine-containing dipeptides, carnosine and anserine: distribution, properties and biological significance
ReviewOther animalsHumans
- Design
- Review
- Subjects
- not applicable
- Dose used in the study
- not applicable
- Duration
- not applicable
- What was measured
- Review of the distribution and metabolism of carnosine and anserine, with attention to their effects on membrane-linked enzyme systems, membrane stability and muscle contractility.
What the authors reported
The authors state that the biological significance of these muscle dipeptides is still open to question. They propose that carnosine and related compounds stabilise biological membranes by interacting with lipid peroxidation products and active oxygen species and preventing membrane damage. They state that this antioxidative effect reflects a high therapeutic value as an anti-inflammatory drug and a tool in wound healing.
Limits of this study
Review; the abstract gives no data for the therapeutic statements, which are the authors' hypothesis. Primary Severin papers from the 1950s are not indexed with abstracts and are not included as separate entries. Full text not read.
Source
PubMed 2206021 · doi:10.1016/0065-2571(90)90017-V
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.