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Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters

Derave W, Ozdemir MS, Harris RC, et al.. Journal of Applied Physiology, 2007; 103(5):1736-1743.

Randomised controlled trialHumansWith beta-alanine (carnosine precursor)

This study tested carnosine together with beta-alanine (carnosine precursor). Its results cannot be assigned to carnosine alone. More combination studies.

Design
Randomised controlled trial
Subjects
15 male 400 m sprint-trained athletes (placebo-controlled, double-blind)
Dose used in the study
4.8 g/day beta-alanine
Duration
4 weeks
What was measured
Soleus and gastrocnemius carnosine by proton MRS; isokinetic knee-extension torque over five bouts; isometric endurance; 400 m race time.

What the authors reported

Beta-alanine raised soleus carnosine by about 47% and gastrocnemius carnosine by about 37%; placebo produced no soleus change and a small gastrocnemius rise of about 16%. Beta-alanine improved dynamic knee-extension torque in the fourth and fifth isokinetic bouts. It did not improve isometric endurance or 400 m race time.

Limits of this study

Small sample; four-week duration. Full text not read.

Source

PubMed 17690198 · doi:10.1152/japplphysiol.00397.2007

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.