Endogenous mechanisms of neuroprotection: role of zinc, copper, and carnosine
Laboratory studyOther animals
- Design
- Laboratory study
- What was measured
- Neuronal survival after exposure to neurotoxic concentrations of zinc or copper, with and without carnosine, in cultured neurons.
What the authors reported
Carnosine rescued neurons from zinc- and copper-mediated neurotoxicity. Building on earlier work showing carnosine modulates the effects of these metals on neuronal excitability, the authors suggest one function of carnosine may be as an endogenous neuroprotective agent.
Limits of this study
Cell culture; culture system, concentrations and effect sizes not stated in abstract. Abstract only.
Source
PubMed 10661495 · doi:10.1016/s0006-8993(99)02215-5
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.