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Monoclonal antibodies to mammalian carnosine synthetase

Margolis FL, Grillo M, Hempstead J, et al.. Journal of Neurochemistry, 1987; 48(2):593-600.

Laboratory studyOther animals

Design
Laboratory study
What was measured
Binding of mouse monoclonal antibodies raised against rabbit muscle carnosine synthetase, and synthetase levels across tissues.

What the authors reported

Four IgG monoclonal antibodies bound carnosine synthetase activity from muscle of all mammals tested (mouse, rat, rabbit, cow, dog, monkey) but not chicken muscle. The immunoassay allowed relative tissue levels to be quantified: high in olfactory tissue of rat and rabbit, generally lower in muscle, brain, heart, liver and gut. Cross-reactivity across tissues of one species suggested similar epitopes.

Limits of this study

Laboratory immunochemistry. Full text not read.

Source

PubMed 3794724 · doi:10.1111/j.1471-4159.1987.tb04134.x

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.