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The effect of carnosine on the healing of a lung wound

Perel'man MI, Kornilova ZK, Paukov VS, et al.. Biulleten' Eksperimental'noi Biologii i Meditsiny, 1989; 108(9):352-356.

Controlled trialOther animals

Design
Controlled trial
Subjects
90 guinea pigs
What was measured
Light and electron microscopy of lung wound repair with and without carnosine.

What the authors reported

Compared with controls, carnosine nearly doubled the speed of reparative processes in the injured guinea pig lung, through activation of fibroblast proliferation, connective tissue generation and intracellular regeneration. Type II epithelial cells formed more osmiophilic and lamellar bodies, and alveolus formation in the wound lips continued by days 7 to 8. The authors link this to faster resolution of atelectasis and restored lung airness.

Limits of this study

Russian-language paper; route and dose not stated in abstract. Full text not read.

Source

PubMed 2611399

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.