Antiglycation and antioxidant effect of carnosine against glucose degradation products in peritoneal mesothelial cells
Laboratory studyOther animals
- Design
- Laboratory study
- What was measured
- Viability, protein carbonyl modification and reactive oxygen species in human peritoneal mesothelial cells incubated with glucose degradation products with or without carnosine for short and prolonged periods.
What the authors reported
Carnosine enhanced cell viability, preserved proteins from carbonyl modification and decreased reactive oxygen species, particularly against glucose degradation product toxicity. The authors proposed carnosine as a candidate for improving peritoneal dialysis fluid biocompatibility.
Limits of this study
Human cells in culture; concentrations not stated in abstract. Full text not read.
Source
PubMed 17664891 · doi:10.1159/000106509
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.