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Evidence for a direct interaction of superoxide anion radical with carnosine

Klebanov GI, Teselkin YO, Babenkova IV, et al.. Biochemistry and Molecular Biology International, 1997; 43(1):99-106.

Laboratory studyOther animals

Design
Laboratory study
What was measured
Luminol photochemiluminescence and a nitro blue tetrazolium assay with a xanthine oxidase superoxide-generating system.

What the authors reported

At physiological concentrations carnosine reduced chemiluminescence amplitude, similar to superoxide dismutase, and prolonged the lag period, similar to ascorbic acid. A rate constant of about 10^5 per molar per second for the carnosine-superoxide reaction was calculated.

Limits of this study

Cell-free chemistry. Full text not read.

Source

PubMed 9315287 · doi:10.1080/15216549700203861

Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.