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Plasmatic levels of carnosine and L-histidine in horses under treadmill standardised exercise

Pacchini S, Ducci M, Baragli P, Basile C, Gazzano A, Sighieri C. Vol 1, p 57.

Observational studyHorses

Design
Observational study
Subjects
not stated in the abstract
Dose used in the study
not applicable (no supplement given)
Duration
two standardised treadmill exercise tests 48 hours apart
What was measured
Plasma carnosine and L-histidine during two standardised treadmill exercise tests; correlation between the two; baseline values before each test.

What the authors reported

The authors report that both compounds rose during each test, with histidine always higher than carnosine. Carnosine changed within the first test (P<0.005); both changed within the second test and between tests (P<0.05). The two were positively correlated within each horse (P<0.05). Baseline values were higher before the second test, which the authors attribute to absent plasma carnosinase and possible subclinical muscle damage in untrained horses. They propose plasma carnosine as a clinical indicator of muscle damage.

Limits of this study

Conference abstract, not a peer-reviewed journal paper. No horse number and no concentrations given.

Source

No PubMed record or DOI. See the citation above.

Entry checked against abstract (University of Pisa repository arpi.unipi.it/handle/11568/112506); also indexed in OpenAlex on 2026-10-11. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.