Applicability of zinc complex of L-carnosine for medical use
ReviewHumansWith zinc (as polaprezinc)
This study tested carnosine together with zinc (as polaprezinc). Its results cannot be assigned to carnosine alone. More combination studies.
- Design
- Review
- What was measured
- Chemistry, mechanism and clinical use of the zinc complex of L-carnosine (polaprezinc) as an anti-ulcer drug.
What the authors reported
Polaprezinc is described as the first oral drug in which zinc has an essential role. Its 1:1 polymeric quadridentate structure resists dissociation in gastric juice, so it adheres to ulcer lesions and releases zinc and carnosine there. The authors report high clinical efficacy, no serious side effects and an inhibitory effect on Helicobacter pylori.
Limits of this study
Narrative review by authors from Hamari Chemicals, a maker of the drug; no quantitative clinical data in the abstract. Full text not read.
Source
Entry checked against PubMed abstract (E-utilities) on 2026-10-19. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.